Survival-associated meQTLs across different cancer types
We identified 23,432 meQTLs associated with patient overall survival across different cancer types at FDR < 0.05.
Cancer type
|
SNP ID
|
SNP position (hg19)
|
Alleles (A/a)
|
log-rank test p-value
|
Sample size
|
Median survival time AA
|
Median survival time Aa
|
Median survival time aa
|
|
---|---|---|---|---|---|---|---|---|---|
KIRC | rs17018511 | chr1:212277604 | C/T | 4.64E-6 | 527 | 42.47 | 31.62 | 17.28 | KM Plot |
KIRC | rs17036071 | chr3:12244544 | A/G | 2.18E-8 | 527 | 2.43 | 43.42 | 38.98 | KM Plot |
KIRC | rs17063398 | chr4:177529309 | A/T | 0 | 522 | 43.3 | 28.98 | 0.6 | KM Plot |
KIRC | rs1710914 | chr10:125309148 | A/G | 5.58E-8 | 527 | 3.37 | 32.73 | 40.8 | KM Plot |
KIRC | rs17135028 | chr6:2431541 | A/G | 3.14E-7 | 527 | 5.23 | 40.78 | 39.7 | KM Plot |
KIRC | rs17136498 | chr7:7754563 | G/A | 3.7E-5 | 521 | 38.1 | 50.27 | 5.47 | KM Plot |
KIRC | rs17169495 | chr7:7727066 | T/C | 6.3E-5 | 525 | 38.88 | 48.48 | 5.47 | KM Plot |
KIRC | rs17169553 | chr7:7739206 | T/C | 5.0E-5 | 526 | 38.47 | 48.63 | 5.47 | KM Plot |
KIRC | rs17178758 | chr21:44298404 | G/A | 3.25E-13 | 523 | 42.75 | 32.42 | 3.37 | KM Plot |
KIRC | rs17178785 | chr21:44301452 | G/A | 3.25E-13 | 523 | 42.75 | 32.42 | 3.37 | KM Plot |
KIRC | rs17182559 | chr21:47703952 | T/C | 3.81E-11 | 517 | 39.08 | 45.55 | 7.4 | KM Plot |
KIRC | rs17306426 | chr11:23222079 | G/T | 3.81E-5 | 527 | 5.6 | 45.17 | 39.53 | KM Plot |
KIRC | rs17586784 | chr6:25935227 | C/A | 2.11E-5 | 522 | 41.27 | 33.82 | 4.1 | KM Plot |
KIRC | rs17587597 | chr6:25986451 | G/A | 4.13E-9 | 517 | 40.6 | 35.7 | 3.37 | KM Plot |
KIRC | rs17608626 | chr6:2395691 | G/A | 3.34E-9 | 519 | 40 | 39.87 | 12.07 | KM Plot |